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Translesion Synthesis Polymerases in the Prevention and Promotion of Carcinogenesis
A critical step in the transformation of cells to the malignant state of cancer is the induction of mutations in the DNA of cells damaged by genotoxic agents. Translesion DNA synthesis (TLS) is the process by which cells copy DNA containing unrepaired damage that blocks progression of the replicatio...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
SAGE-Hindawi Access to Research
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2945679/ https://ncbi.nlm.nih.gov/pubmed/20936171 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4061/2010/643857 |
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