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Kinetic Properties and Functional Dynamics of Sodium Channels during Repetitive Spiking in a Slow Pacemaker Neuron

We examined the kinetic properties of voltage-gated Na(+) channels and their contribution to the repetitive spiking activity of medullary raphé neurons, which exhibit slow pacemaking and strong spiking adaptation. The study is based on a combination of whole-cell patch-clamp, modeling and real-time...

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Main Authors: Milescu, Lorin S., Yamanishi, Tadashi, Ptak, Krzysztof, Smith, Jeffrey C.
格式: Artigo
語言:Inglês
出版: Society for Neuroscience 2010
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2945634/
https://ncbi.nlm.nih.gov/pubmed/20826674
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0445-10.2010
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