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Kinetic properties of persistent Na(+) current orchestrate oscillatory bursting in respiratory neurons

The rhythmic pattern of breathing depends on the pre-Bötzinger complex (preBötC) in the brainstem, a vital circuit that contains a population of neurons with intrinsic oscillatory bursting behavior. Here, we investigate the specific kinetic properties that enable voltage-gated sodium channels to est...

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Détails bibliographiques
Publié dans:J Gen Physiol
Auteurs principaux: Yamanishi, Tadashi, Koizumi, Hidehiko, Navarro, Marco A., Milescu, Lorin S., Smith, Jeffrey C.
Format: Artigo
Langue:Inglês
Publié: Rockefeller University Press 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6219691/
https://ncbi.nlm.nih.gov/pubmed/30301870
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.201812100
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