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Viral Evolution and Escape during Acute HIV-1 Infection

The extensive genetic diversity of HIV-1 presents a significant barrier to the development of an effective and durable HIV vaccine. This variability not only makes it difficult to identify the targets against which immune responses should be directed, but it also confers on the virus the capacity fo...

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Detalles Bibliográficos
Main Authors: Boutwell, Christian L., Rolland, Morgane M., Herbeck, Joshua T., Mullins, James I., Allen, Todd M.
Formato: Artigo
Idioma:Inglês
Publicado: 2010
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2945609/
https://ncbi.nlm.nih.gov/pubmed/20846038
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1086/655653
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