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Schwann Cell Dedifferentiation Is Independent of Mitogenic Signaling and Uncoupled to Proliferation: ROLE OF cAMP AND JNK IN THE MAINTENANCE OF THE DIFFERENTIATED STATE

Myelinating Schwann cells (SCs) are highly plastic cells that are able to dedifferentiate and re-enter the cell cycle. However, the molecular signals controlling dedifferentiation are not completely understood. Because a connection between mitogenic signaling and myelin loss has been suggested, we i...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Monje, Paula V., Soto, Jennifer, Bacallao, Ketty, Wood, Patrick M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2945593/
https://ncbi.nlm.nih.gov/pubmed/20634285
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.116970
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