Synergistic Allostery, a Sophisticated Regulatory Network for the Control of Aromatic Amino Acid Biosynthesis in Mycobacterium tuberculosis

The shikimate pathway, responsible for aromatic amino acid biosynthesis, is required for the growth of Mycobacterium tuberculosis and is a potential drug target. The first reaction is catalyzed by 3-deoxy-d-arabino-heptulosonate 7-phosphate synthase (DAH7PS). Feedback regulation of DAH7PS activity b...

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Detaylı Bibliyografya
Asıl Yazarlar: Webby, Celia J., Jiao, Wanting, Hutton, Richard D., Blackmore, Nicola J., Baker, Heather M., Baker, Edward N., Jameson, Geoffrey B., Parker, Emily J.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Society for Biochemistry and Molecular Biology 2010
Konular:
Enzymology
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2945551/
https://ncbi.nlm.nih.gov/pubmed/20667835
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.111856
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