Effects of glucose on sorbitol pathway activation, cellular redox, and metabolism of myo-inositol, phosphoinositide, and diacylglycerol in cultured human retinal pigment epithelial cells.

Sorbitol (aldose reductase) pathway flux in diabetes perturbs intracellular metabolism by two putative mechanisms: reciprocal osmoregulatory depletion of other organic osmolytes e.g., myo-inositol, and alterations in NADPH/NADP+ and/or NADH/NAD+. The "osmolyte" and "redox" hypotheses predict seconda...

詳細記述

保存先:

書誌詳細
出版年:	J Clin Invest
主要な著者:	Thomas, T P, Porcellati, F, Kato, K, Stevens, M J, Sherman, W R, Greene, D A
フォーマット:	Artigo
言語:	Inglês
出版事項:	American Society for Clinical Investigation 1994
主題:	Research Article
オンライン･アクセス:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC294524/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8201009/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI117286
タグ:	タグ追加タグなし, このレコードへの初めてのタグを付けませんか!

Effects of glucose on sorbitol pathway activation, cellular redox, and metabolism of myo-inositol, phosphoinositide, and diacylglycerol in cultured human retinal pigment epithelial cells.

類似資料