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Evaluation of innate immunity and vector toxicity following inoculation of bovine, porcine or human adenoviral vectors in a mouse model

Nonhuman adenovirus (Ad) vectors derived from bovine Ad serotype 3 (BAd3) or porcine Ad serotype 3 (PAd3) can circumvent pre-existing immunity against human Ad (HAd). We have previously reported differential transduction of human and nonhuman cells by these Ad vectors, and their distinct receptor us...

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Main Authors: Sharma, Anurag, Bangari, Dinesh S., Tandon, Manish, HogenEsch, Harm, Mittal, Suresh K.
格式: Artigo
語言:Inglês
出版: 2010
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2945211/
https://ncbi.nlm.nih.gov/pubmed/20659505
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virusres.2010.07.021
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