Human Papillomavirus 16 E6 Variants Differ in their Dysregulation of Human Keratinocyte Differentiation and Apoptosis

L83V–related variants of human papillomavirus (HPV) 16 E6, exemplified by the Asian-American variant Q14H/H78Y/L83V, were shown to be more prevalent than E6 prototype in progressing lesions and cervical cancer. We evaluated functions relevant to carcinogenesis for the E6 variants L83V, R10/L83V and...

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Detalhes bibliográficos
Main Authors: Zehbe, Ingeborg, Richard, Christina, DeCarlo, Correne A., Shai, Anny, Lambert, Paul F., Lichtig, Hava, Tommasino, Massimo, Sherman, Levana
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2945146/
https://ncbi.nlm.nih.gov/pubmed/18986660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2008.09.036
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