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Sonoporation Delivery of Monoclonal Antibodies against Human Papillomavirus 16 E6 Restores p53 Expression in Transformed Cervical Keratinocytes

High-risk types of human papillomavirus (HPV), such as HPV16, have been found in nearly all cases of cervical cancer. Therapies targeted at blocking the HPV16 E6 protein and its deleterious effects on the tumour suppressor pathways of the cell can reverse the malignant phenotype of affected keratino...

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Detalhes bibliográficos
Main Authors: Togtema, Melissa, Pichardo, Samuel, Jackson, Robert, Lambert, Paul F., Curiel, Laura, Zehbe, Ingeborg
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3511358/
https://ncbi.nlm.nih.gov/pubmed/23226365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0050730
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