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Role of controlled cardiac reoxygenation in reducing nitric oxide production and cardiac oxidant damage in cyanotic infantile hearts.

Cardiopulmonary bypass (CPB) is used increasingly to correct cyanotic heart defects during early infancy, but myocardial dysfunction is often seen after surgical repair. This study evaluates whether starting CPB at a conventional, hyperoxic pO2 causes an "unintentional" reoxygenation (ReO2) injury....

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Vydáno v:J Clin Invest
Hlavní autoři: Morita, K, Ihnken, K, Buckberg, G D, Sherman, M P, Young, H H, Ignarro, L J
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Clinical Investigation 1994
Témata:
On-line přístup:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC294509/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8201004/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI117279
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