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Role of controlled cardiac reoxygenation in reducing nitric oxide production and cardiac oxidant damage in cyanotic infantile hearts.

Cardiopulmonary bypass (CPB) is used increasingly to correct cyanotic heart defects during early infancy, but myocardial dysfunction is often seen after surgical repair. This study evaluates whether starting CPB at a conventional, hyperoxic pO2 causes an "unintentional" reoxygenation (ReO2) injury....

Ausführliche Beschreibung

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Bibliografische Detailangaben
Veröffentlicht in:J Clin Invest
Hauptverfasser: Morita, K, Ihnken, K, Buckberg, G D, Sherman, M P, Young, H H, Ignarro, L J
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Clinical Investigation 1994
Schlagworte:
Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC294509/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8201004/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI117279
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