Role of controlled cardiac reoxygenation in reducing nitric oxide production and cardiac oxidant damage in cyanotic infantile hearts.

Cardiopulmonary bypass (CPB) is used increasingly to correct cyanotic heart defects during early infancy, but myocardial dysfunction is often seen after surgical repair. This study evaluates whether starting CPB at a conventional, hyperoxic pO2 causes an "unintentional" reoxygenation (ReO2) injury....

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Bibliographic Details

Published in:	J Clin Invest
Main Authors:	Morita, K, Ihnken, K, Buckberg, G D, Sherman, M P, Young, H H, Ignarro, L J
Format:	Artigo
Language:	Inglês
Published:	American Society for Clinical Investigation 1994
Subjects:	Research Article
Online Access:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC294509/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8201004/ https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI117279
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