Insufficient β-lactam concentrations in the early phase of severe sepsis and septic shock

INTRODUCTION: Altered pharmacokinetics (PK) in critically ill patients can result in insufficient serum β-lactam concentrations when standard dosages are administered. Previous studies on β-lactam PK have generally excluded the most severely ill patients, or were conducted during the steady-state pe...

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Detalhes bibliográficos
Main Authors: Taccone, Fabio Silvio, Laterre, Pierre-François, Dugernier, Thierry, Spapen, Herbert, Delattre, Isabelle, Wittebole, Xavier, De Backer, Daniel, Layeux, Brice, Wallemacq, Pierre, Vincent, Jean-Louis, Jacobs, Frédérique
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2010
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2945087/
https://ncbi.nlm.nih.gov/pubmed/20594297
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/cc9091
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