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β2-Syntrophin Is a Cdk5 Substrate That Restrains the Motility of Insulin Secretory Granules
The molecular basis for the interaction of insulin granules with the cortical cytoskeleton of pancreatic β-cells remains unknown. We have proposed that binding of the granule protein ICA512 to the PDZ domain of β2-syntrophin anchors granules to actin filaments and that the phosphorylation/dephosphor...
में बचाया:
| मुख्य लेखकों: | , , , , , , , , , , , , , |
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| स्वरूप: | Artigo |
| भाषा: | Inglês |
| प्रकाशित: |
Public Library of Science
2010
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| विषय: | |
| ऑनलाइन पहुंच: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2944849/ https://ncbi.nlm.nih.gov/pubmed/20886068 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0012929 |
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