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In vivo requirement of the α-syntrophin PDZ domain for the sarcolemmal localization of nNOS and aquaporin-4

α-Syntrophin is a scaffolding adapter protein expressed primarily on the sarcolemma of skeletal muscle. The COOH-terminal half of α-syntrophin binds to dystrophin and related proteins, leaving the PSD-95, discs-large, ZO-1 (PDZ) domain free to recruit other proteins to the dystrophin complex. We inv...

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Bibliografische gegevens
Hoofdauteurs: Adams, Marvin E., Mueller, Heather A., Froehner, Stanley C.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: The Rockefeller University Press 2001
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2150783/
https://ncbi.nlm.nih.gov/pubmed/11571312
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200106158
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