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Matrix Rigidity Regulates Cancer Cell Growth and Cellular Phenotype

BACKGROUND: The mechanical properties of the extracellular matrix have an important role in cell growth and differentiation. However, it is unclear as to what extent cancer cells respond to changes in the mechanical properties (rigidity/stiffness) of the microenvironment and how this response varies...

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Autori principali: Tilghman, Robert W., Cowan, Catharine R., Mih, Justin D., Koryakina, Yulia, Gioeli, Daniel, Slack-Davis, Jill K., Blackman, Brett R., Tschumperlin, Daniel J., Parsons, J. Thomas
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2944843/
https://ncbi.nlm.nih.gov/pubmed/20886123
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0012905
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