Matrix Rigidity Regulates Cancer Cell Growth by Modulating Cellular Metabolism and Protein Synthesis

BACKGROUND: Tumor cells in vivo encounter diverse types of microenvironments both at the site of the primary tumor and at sites of distant metastases. Understanding how the various mechanical properties of these microenvironments affect the biology of tumor cells during disease progression is critic...

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Autors principals: Tilghman, Robert W., Blais, Edik M., Cowan, Catharine R., Sherman, Nicholas E., Grigera, Pablo R., Jeffery, Erin D., Fox, Jay W., Blackman, Brett R., Tschumperlin, Daniel J., Papin, Jason A., Parsons, J. Thomas
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2012
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3356407/
https://ncbi.nlm.nih.gov/pubmed/22623999
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0037231
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