Matrix Rigidity Regulates Cancer Cell Growth and Cellular Phenotype

BACKGROUND: The mechanical properties of the extracellular matrix have an important role in cell growth and differentiation. However, it is unclear as to what extent cancer cells respond to changes in the mechanical properties (rigidity/stiffness) of the microenvironment and how this response varies...

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Detalhes bibliográficos
Main Authors: Tilghman, Robert W., Cowan, Catharine R., Mih, Justin D., Koryakina, Yulia, Gioeli, Daniel, Slack-Davis, Jill K., Blackman, Brett R., Tschumperlin, Daniel J., Parsons, J. Thomas
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2944843/
https://ncbi.nlm.nih.gov/pubmed/20886123
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0012905
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