Pathogen Specific, IRF3-Dependent Signaling and Innate Resistance to Human Kidney Infection

The mucosal immune system identifies and fights invading pathogens, while allowing non-pathogenic organisms to persist. Mechanisms of pathogen/non-pathogen discrimination are poorly understood, as is the contribution of human genetic variation in disease susceptibility. We describe here a new, IRF3-...

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Detalhes bibliográficos
Main Authors: Fischer, Hans, Lutay, Nataliya, Ragnarsdóttir, Bryndís, Yadav, Manisha, Jönsson, Klas, Urbano, Alexander, Al Hadad, Ahmed, Rämisch, Sebastian, Storm, Petter, Dobrindt, Ulrich, Salvador, Ellaine, Karpman, Diana, Jodal, Ulf, Svanborg, Catharina
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2010
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2944801/
https://ncbi.nlm.nih.gov/pubmed/20886096
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1001109
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