Acute pyelonephritis and renal scarring are caused by dysfunctional innate immunity in mCxcr2 heterozygous mice

The CXCR1 receptor and chemokine CXCL8 (IL-8) support neutrophil-dependent clearance of uropathogenic Escherichia coli from the urinary tract. CXCR1 is reduced in children prone to pyelonephritis, and heterozygous hCXCR1 polymorphisms are more common in this patient group than in healthy individuals...

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Detaylı Bibliyografya
Asıl Yazarlar: Svensson, Majlis, Yadav, Manisha, Holmqvist, Bo, Lutay, Nataliya, Svanborg, Catharina, Godaly, Gabriela
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Nature Publishing Group 2011
Konular:
Original Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3257042/
https://ncbi.nlm.nih.gov/pubmed/21814172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ki.2011.257
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