Acute pyelonephritis and renal scarring are caused by dysfunctional innate immunity in mCxcr2 heterozygous mice

The CXCR1 receptor and chemokine CXCL8 (IL-8) support neutrophil-dependent clearance of uropathogenic Escherichia coli from the urinary tract. CXCR1 is reduced in children prone to pyelonephritis, and heterozygous hCXCR1 polymorphisms are more common in this patient group than in healthy individuals...

Cijeli opis

Spremljeno u:
Bibliografski detalji
Glavni autori: Svensson, Majlis, Yadav, Manisha, Holmqvist, Bo, Lutay, Nataliya, Svanborg, Catharina, Godaly, Gabriela
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group 2011
Teme:
Original Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3257042/
https://ncbi.nlm.nih.gov/pubmed/21814172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ki.2011.257
Oznake: Dodaj oznaku
Bez oznaka, Budi prvi tko označuje ovaj zapis!

Similar Items