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Pertussis toxin treatment alters manganese superoxide dismutase activity in lung. Evidence for lung oxygen toxicity in air-breathing rats.

Exposure of rats to hyperoxia or to treatment with endotoxin, increases lung manganese superoxide dismutase (MnSOD) gene expression. However, the paths by which these environmental signals are transduced into enhanced MnSOD gene expression are unknown. We now provide evidence that heterotrimeric G p...

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Detalhes bibliográficos
Publicado no:J Clin Invest
Main Authors: Clerch, L B, Neithardt, G, Spencer, U, Melendez, J A, Massaro, G D, Massaro, D
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 1994
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC294460/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8200984/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI117257
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