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Pertussis toxin treatment alters manganese superoxide dismutase activity in lung. Evidence for lung oxygen toxicity in air-breathing rats.

Exposure of rats to hyperoxia or to treatment with endotoxin, increases lung manganese superoxide dismutase (MnSOD) gene expression. However, the paths by which these environmental signals are transduced into enhanced MnSOD gene expression are unknown. We now provide evidence that heterotrimeric G p...

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Bibliographic Details
Main Authors: Clerch, L B, Neithardt, G, Spencer, U, Melendez, J A, Massaro, G D, Massaro, D
Format: Artigo
Language:Inglês
Published: 1994
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC294460/
https://ncbi.nlm.nih.gov/pubmed/8200984
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