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Pertussis toxin treatment alters manganese superoxide dismutase activity in lung. Evidence for lung oxygen toxicity in air-breathing rats.

Exposure of rats to hyperoxia or to treatment with endotoxin, increases lung manganese superoxide dismutase (MnSOD) gene expression. However, the paths by which these environmental signals are transduced into enhanced MnSOD gene expression are unknown. We now provide evidence that heterotrimeric G p...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:J Clin Invest
Hauptverfasser: Clerch, L B, Neithardt, G, Spencer, U, Melendez, J A, Massaro, G D, Massaro, D
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Clinical Investigation 1994
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC294460/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8200984/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI117257
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