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Lysyl-Phosphatidylglycerol Attenuates Membrane Perturbation Rather than Surface Association of the Cationic Antimicrobial Peptide 6W-RP-1 in a Model Membrane System: Implications for Daptomycin Resistance

The presence of the cationic phospholipid lysyl-phosphatidylglycerol (lysyl-PG) in staphylococcal cytoplasmic membranes has been linked to increased resistance to cationic compounds, including antibiotics such as daptomycin as well as host defense antimicrobial peptides. We investigated the effects...

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Detalhes bibliográficos
Main Authors: Kilelee, Erin, Pokorny, Antje, Yeaman, Michael R., Bayer, Arnold S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2944598/
https://ncbi.nlm.nih.gov/pubmed/20660664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00191-10
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