Impact of Burden on Granulocyte Clearance of Bacteria in a Mouse Thigh Infection Model

We wished to delineate granulocytes' impact on the clearance of different bacterial burdens of Pseudomonas aeruginosa and Staphylococcus aureus in a granulocyte-replete mouse thigh infection model. A mouse thigh model was employed. Bacterial challenges from 10(5) to 3 × 10(7) CFU (S. aureus) an...

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Hauptverfasser: Drusano, G. L., Fregeau, Christine, Liu, Weiguo, Brown, D. L., Louie, Arnold
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 2010
Schlagworte:
Experimental Therapeutics
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2944594/
https://ncbi.nlm.nih.gov/pubmed/20516275
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00133-10
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