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Once-Weekly Micafungin Therapy Is as Effective as Daily Therapy for Disseminated Candidiasis in Mice with Persistent Neutropenia

The effect of micafungin dose scheduling on the treatment of candidemia is unknown. Neutropenic mice with disseminated Candida glabrata infection were treated with single intraperitoneal micafungin doses of 0 to 100 mg/kg of body weight and sacrificed 7 days later. The maximal decline in kidney fung...

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Détails bibliographiques
Auteurs principaux: Gumbo, Tawanda, Drusano, George L., Liu, Weiguo, Kulawy, Robert W., Fregeau, Christine, Hsu, Vasha, Louie, Arnold
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2007
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1803141/
https://ncbi.nlm.nih.gov/pubmed/17194830
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01337-06
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