Evaluation of Once-Daily Vancomycin against Methicillin-Resistant Staphylococcus aureus in a Hollow-Fiber Infection Model

For methicillin-resistant Staphylococcus aureus (MRSA) infections, data suggest that the clinical response is significantly better if the total vancomycin area under the concentration-time curve (AUC)/MIC ratio is ≥400. While the AUC/MIC ratio is the accepted pharmacokinetic/pharmacodynamic (PK/PD)...

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Detalhes bibliográficos
Main Authors: Nicasio, Anthony M., Bulitta, Jürgen B., Lodise, Thomas P., D'Hondt, Rebecca E., Kulawy, Robert, Louie, Arnold, Drusano, George L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2012
Assuntos:
Experimental Therapeutics
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3264248/
https://ncbi.nlm.nih.gov/pubmed/22083484
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.05664-11
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