Short Cationic Antimicrobial Peptides Interact with ATP

The mode of action of short, nonhelical antimicrobial peptides is still not well understood. Here we show that these peptides interact with ATP and directly inhibit the actions of certain ATP-dependent enzymes, such as firefly luciferase, DnaK, and DNA polymerase. α-Helical and planar or circular an...

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Bibliographic Details
Main Authors: Hilpert, Kai, McLeod, Brett, Yu, Jessie, Elliott, Melissa R., Rautenbach, Marina, Ruden, Serge, Bürck, Jochen, Muhle-Goll, Claudia, Ulrich, Anne S., Keller, Sandro, Hancock, Robert E. W.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology (ASM) 2010
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Mechanisms of Action: Physiological Effects
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2944583/
https://ncbi.nlm.nih.gov/pubmed/20660668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01664-09
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