Short Cationic Antimicrobial Peptides Interact with ATP

The mode of action of short, nonhelical antimicrobial peptides is still not well understood. Here we show that these peptides interact with ATP and directly inhibit the actions of certain ATP-dependent enzymes, such as firefly luciferase, DnaK, and DNA polymerase. α-Helical and planar or circular an...

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Autori principali: Hilpert, Kai, McLeod, Brett, Yu, Jessie, Elliott, Melissa R., Rautenbach, Marina, Ruden, Serge, Bürck, Jochen, Muhle-Goll, Claudia, Ulrich, Anne S., Keller, Sandro, Hancock, Robert E. W.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology (ASM) 2010
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Mechanisms of Action: Physiological Effects
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2944583/
https://ncbi.nlm.nih.gov/pubmed/20660668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01664-09
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