Short Cationic Antimicrobial Peptides Interact with ATP

The mode of action of short, nonhelical antimicrobial peptides is still not well understood. Here we show that these peptides interact with ATP and directly inhibit the actions of certain ATP-dependent enzymes, such as firefly luciferase, DnaK, and DNA polymerase. α-Helical and planar or circular an...

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Hauptverfasser: Hilpert, Kai, McLeod, Brett, Yu, Jessie, Elliott, Melissa R., Rautenbach, Marina, Ruden, Serge, Bürck, Jochen, Muhle-Goll, Claudia, Ulrich, Anne S., Keller, Sandro, Hancock, Robert E. W.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 2010
Schlagworte:
Mechanisms of Action: Physiological Effects
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2944583/
https://ncbi.nlm.nih.gov/pubmed/20660668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01664-09
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