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Efficacy of Daptomycin against Bacillus anthracis in a Murine Model of Anthrax Spore Inhalation

Daptomycin demonstrated in vitro (MIC(90), 4 μg/ml) and in vivo activities against Bacillus anthracis. Twice-daily treatment with a dose of 50 mg/kg of body weight was begun 24 h after challenge and continued for 14 or 21 days; results were compared to those for controls treated with phosphate-buffe...

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Main Authors: Heine, Henry S., Bassett, Jennifer, Miller, Lynda, Purcell, Bret K., Byrne, W. Russell
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology (ASM) 2010
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2944578/
https://ncbi.nlm.nih.gov/pubmed/20643899
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00210-10
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