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Determination of Antibiotic Efficacy against Bacillus anthracis in a Mouse Aerosol Challenge Model
An anthrax spore aerosol infection mouse model was developed as a first test of in vivo efficacy of antibiotics identified as active against Bacillus anthracis. Whole-body, 50% lethal dose (LD(50)) aerosol challenge doses in a range of 1.9 × 10(3) to 3.4 × 10(4) CFU with spores of the fully virulent...
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| Autori principali: | , , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
American Society for Microbiology
2007
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1855446/ https://ncbi.nlm.nih.gov/pubmed/17296745 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01050-06 |
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