Tachybradycardia in the isolated canine right atrium induced by chronic sympathetic stimulation and pacemaker current inhibition

The mechanisms of sinoatrial node (SAN) dysfunction in patients with chronically elevated sympathetic tone and reduced pacemaker current (I(f); such as heart failure) are poorly understood. We simultaneously mapped membrane potential and intracellular Ca(2+) in the Langendorff-perfused canine right...

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Bibliografiske detaljer
Main Authors: Joung, Boyoung, Shinohara, Tetsuji, Zhang, Hong, Kim, Daehyeok, Choi, Eue-Keun, On, Yong-Keun, Piccirillo, Gianfranco, Chen, Peng-Sheng, Lin, Shien-Fong
Format: Artigo
Sprog:Inglês
Udgivet: American Physiological Society 2010
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Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2944487/
https://ncbi.nlm.nih.gov/pubmed/20601460
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00347.2010
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