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Tachybradycardia in the isolated canine right atrium induced by chronic sympathetic stimulation and pacemaker current inhibition

The mechanisms of sinoatrial node (SAN) dysfunction in patients with chronically elevated sympathetic tone and reduced pacemaker current (I(f); such as heart failure) are poorly understood. We simultaneously mapped membrane potential and intracellular Ca(2+) in the Langendorff-perfused canine right...

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Detalhes bibliográficos
Main Authors: Joung, Boyoung, Shinohara, Tetsuji, Zhang, Hong, Kim, Daehyeok, Choi, Eue-Keun, On, Yong-Keun, Piccirillo, Gianfranco, Chen, Peng-Sheng, Lin, Shien-Fong
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2944487/
https://ncbi.nlm.nih.gov/pubmed/20601460
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00347.2010
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