Effects of cardiac overexpression of type 6 adenylyl cyclase affects on the response to chronic pressure overload

Adenylyl cyclase (AC) type 5 (AC5) and AC type 6 (AC6) are the two major AC isoforms in the heart. Cardiac overexpression of AC6 has been shown to be protective in response to several interventions. In this investigation, we examined the effects of chronic pressure overload in AC6 transgenic (TG) mi...

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Hauptverfasser: Guellich, Aziz, Gao, Shumin, Hong, Chull, Yan, Lin, Wagner, Thomas E., Dhar, Sunil K., Ghaleh, Bijan, Hittinger, Luc, Iwatsubo, Kosaku, Ishikawa, Yoshihiro, Vatner, Stephen F., Vatner, Dorothy E.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Physiological Society 2010
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2944475/
https://ncbi.nlm.nih.gov/pubmed/20562336
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpheart.00148.2010
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