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Nerve Growth Factor Induces Axonal Filopodia through Localized Microdomains of Phosphoinositide 3-Kinase Activity That Drive the Formation of Cytoskeletal Precursors to Filopodia

The initiation of axonal filopodia is the first step in the formation of collateral branches and synaptic structures. In sensory neurons, nerve growth factor (NGF) promotes the formation of axonal filopodia and branches. However, the signaling and cytoskeletal mechanisms of NGF-induced initiation of...

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Autors principals: Ketschek, Andrea, Gallo, Gianluca
Format: Artigo
Idioma:Inglês
Publicat: Society for Neuroscience 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2944214/
https://ncbi.nlm.nih.gov/pubmed/20826681
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1740-10.2010
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