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Mitochondria Coordinate Sites of Axon Branching through Localized Intra-Axonal Protein Synthesis

The branching of axons is a fundamental aspect of nervous system development and neuroplasticity. We report that branching of sensory axons in the presence of NGF occurs at sites populated by stalled mitochondria. Translational machinery targets to presumptive branching sites, followed by recruitmen...

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Detalhes bibliográficos
Main Authors: Spillane, Mirela, Ketschek, Andrea, Merianda, Tanuja T., Twiss, Jeffery L., Gallo, Gianluca
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3947524/
https://ncbi.nlm.nih.gov/pubmed/24332852
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2013.11.022
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