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Mitochondria Coordinate Sites of Axon Branching through Localized Intra-Axonal Protein Synthesis

The branching of axons is a fundamental aspect of nervous system development and neuroplasticity. We report that branching of sensory axons in the presence of NGF occurs at sites populated by stalled mitochondria. Translational machinery targets to presumptive branching sites, followed by recruitmen...

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Détails bibliographiques
Auteurs principaux: Spillane, Mirela, Ketschek, Andrea, Merianda, Tanuja T., Twiss, Jeffery L., Gallo, Gianluca
Format: Artigo
Langue:Inglês
Publié: 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3947524/
https://ncbi.nlm.nih.gov/pubmed/24332852
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2013.11.022
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