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The Actin Nucleating Arp2/3 Complex Contributes to the Formation of Axonal Filopodia and Branches Through the Regulation of Actin Patch Precursors to Filopodia

The emergence of axonal filopodia is the first step in the formation of axon collateral branches. In vitro, axonal filopodia emerge from precursor cytoskeletal structures termed actin patches. However, nothing is known about the cytoskeletal dynamics of the axon leading to the formation of filopodia...

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Detalhes bibliográficos
Main Authors: Spillane, Mirela, Ketschek, Andrea, Jones, Steven L., Korobova, Farida, Marsick, Bonnie, Lanier, Lorene, Svitkina, Tatyana, Gallo, Gianluca
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3154400/
https://ncbi.nlm.nih.gov/pubmed/21557512
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/dneu.20907
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