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The Actin Nucleating Arp2/3 Complex Contributes to the Formation of Axonal Filopodia and Branches Through the Regulation of Actin Patch Precursors to Filopodia

The emergence of axonal filopodia is the first step in the formation of axon collateral branches. In vitro, axonal filopodia emerge from precursor cytoskeletal structures termed actin patches. However, nothing is known about the cytoskeletal dynamics of the axon leading to the formation of filopodia...

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Détails bibliographiques
Auteurs principaux: Spillane, Mirela, Ketschek, Andrea, Jones, Steven L., Korobova, Farida, Marsick, Bonnie, Lanier, Lorene, Svitkina, Tatyana, Gallo, Gianluca
Format: Artigo
Langue:Inglês
Publié: 2011
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3154400/
https://ncbi.nlm.nih.gov/pubmed/21557512
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/dneu.20907
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