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Increased Resorptive Activity and Accompanying Morphological Alterations in Osteoclasts Derived From the Oim/Oim Mouse Model of Osteogenesis Imperfecta

The current study addresses whether alterations in osteoclasts (OCs) derived from oim/oim mice, an established model of moderate-to-severe OI, are present. Bone marrow cells from oim/oim and wildtype (+/+) mice were cultured on bone slices in the presence of MCSF and RANKL and evaluated at days 0, 1...

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Detalhes bibliográficos
Main Authors: Zhang, Hao, Doty, Stephen B., Hughes, Christine, Dempster, David, Camacho, Nancy Pleshko
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2944034/
https://ncbi.nlm.nih.gov/pubmed/17668424
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcb.21337
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