Skeletal muscle specific mitochondrial dysfunction and altered energy metabolism in a murine model (oim/oim) of severe osteogenesis imperfecta

Osteogenesis imperfecta (OI) is a heritable connective tissue disorder with patients exhibiting bone fragility and muscle weakness. The synergistic biochemical and biomechanical relationship between bone and muscle is a critical potential therapeutic target, such that muscle weakness should not be i...

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Bibliographic Details
Published in:Mol Genet Metab
Main Authors: Gremminger, Victoria L., Harrelson, Emily N., Crawford, Tara K., Ohler, Adrienne, Schulz, Laura C., Rector, R. Scott, Phillips, Charlotte L.
Format: Artigo
Language:Inglês
Published: 2021
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8135105/
https://ncbi.nlm.nih.gov/pubmed/33674196
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymgme.2021.02.004
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