Loss of RANKL in osteocytes dramatically increases cancellous bone mass in the osteogenesis imperfecta mouse (oim)

Osteogenesis imperfecta (OI) is characterized by osteopenia and bone fragility, and OI patients during growth often exhibit high bone turnover with the net result of low bone mass. Recent evidence shows that osteocytes significantly affect bone remodeling under physiological and pathological conditi...

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Опубликовано в: :Bone Rep
Главные авторы: Zimmerman, Sarah M., Heard-Lipsmeyer, Melissa E., Dimori, Milena, Thostenson, Jeff D., Mannen, Erin M., O'Brien, Charles A., Morello, Roy
Формат: Artigo
Язык:Inglês
Опубликовано: Elsevier 2018
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6077550/
https://ncbi.nlm.nih.gov/pubmed/30105276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bonr.2018.06.008
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