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Loss of RANKL in osteocytes dramatically increases cancellous bone mass in the osteogenesis imperfecta mouse (oim)

Osteogenesis imperfecta (OI) is characterized by osteopenia and bone fragility, and OI patients during growth often exhibit high bone turnover with the net result of low bone mass. Recent evidence shows that osteocytes significantly affect bone remodeling under physiological and pathological conditi...

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Detalhes bibliográficos
Publicado no:Bone Rep
Main Authors: Zimmerman, Sarah M., Heard-Lipsmeyer, Melissa E., Dimori, Milena, Thostenson, Jeff D., Mannen, Erin M., O'Brien, Charles A., Morello, Roy
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6077550/
https://ncbi.nlm.nih.gov/pubmed/30105276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bonr.2018.06.008
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