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Cation-dependent cleavage of the duplex form of the subtype-B HIV-1 RNA dimerization initiation site
The crystal structure of subtype-B HIV-1 genomic RNA Dimerization Initiation Site duplex revealed chain cleavage at a specific position resulting in 3′-phosphate and 5′-hydroxyl termini. A crystallographic analysis showed that Ba(2+), Mn(2+), Co(2+) and Zn(2+) bind specifically on a guanine base clo...
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| Main Authors: | , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Oxford University Press
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2943608/ https://ncbi.nlm.nih.gov/pubmed/20460458 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkq344 |
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