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Anoikis triggers Mdm2-dependent p53 degradation

The extracellular matrix (ECM) plays a key role in cell–cell communication and signaling, and the signals it propagates are important for tissue remodeling and survival. However, signals from disease-altered ECM may lead to anoikis—apoptotic cell death triggered by loss of ECM contacts. Previously,...

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Main Authors: Ghosh, Abhijit, Chen, Tina Chunyuan, Kapila, Yvonne L.
Formato: Artigo
Idioma:Inglês
Publicado: 2010
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2943547/
https://ncbi.nlm.nih.gov/pubmed/20577896
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11010-010-0514-6
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