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Proapoptotic fibronectin fragment induces the degradation of ubiquitinated p53 via proteasomes in periodontal ligament cells

BACKGROUND AND OBJECTIVE: The extracellular matrix (ECM) plays a key role in signaling necessary for tissue remodeling and cell survival. However, signals from disease-altered ECMs, as that present in inflammatory diseases like periodontitis and arthritis, may lead to apoptosis or programmed cell de...

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Hlavní autoři: Ghosh, Abhijit, Joo, Nam Eok, Chen, Tina Chunyuan, Kapila, Yvonne L.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2894266/
https://ncbi.nlm.nih.gov/pubmed/20337881
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1600-0765.2009.01261.x
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