Phosphatidylinositol 3-Kinase Regulates Macrophage Responses to Double-Stranded RNA and Encephalomyocarditis Virus

Virus infection of macrophages stimulates the expression of proinflammatory and antiviral genes interleukin-1 (IL-1), inducible nitric oxide synthase (iNOS) and cyclooxygenase-2 (COX-2). In this study, we show that phosphatidylinositol 3-kinase (PI3K) is required for the inflammatory response of mac...

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Main Authors: Freudenburg, Wieke, Moran, Jason M., Lents, Nathan H., Baldassare, Joseph J., Buller, R. Mark L., Corbett, John A.
格式: Artigo
語言:Inglês
出版: S. Karger AG 2009
主題:
Research Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2943520/
https://ncbi.nlm.nih.gov/pubmed/20375625
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000243785
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