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Potential role of PKR in double-stranded RNA-induced macrophage activation

In this study, the role of the double-stranded (ds) RNA-dependent protein kinase (PKR) in macrophage activation was examined. dsRNA [polyinosinic:polycytidylic acid (poly IC)]-stimulated inducible nitric oxide synthase, interleukin (IL)-1α and IL-1β mRNA expression, nitrite formation and IL-1 releas...

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Detalhes bibliográficos
Main Authors: Maggi, Leonard B., Heitmeier, Monique R., Scheuner, Donalyn, Kaufman, Randal J., Buller, R.Mark L., Corbett, John A.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2000
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC313973/
https://ncbi.nlm.nih.gov/pubmed/10899117
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/19.14.3630
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