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A general chemical method to regulate protein stability in the mammalian central nervous system
The ability to make specific perturbations to biological molecules in a cell or organism is a central experimental strategy in modern research biology. We have developed a general technique in which the stability of a specific protein is regulated by a cell-permeable small molecule. Mutants of the E...
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| Autors principals: | , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2010
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2943492/ https://ncbi.nlm.nih.gov/pubmed/20851347 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chembiol.2010.07.009 |
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