NPM1 Deletion Is Associated with Gross Chromosomal Rearrangements in Leukemia

BACKGROUND: NPM1 gene at chromosome 5q35 is involved in recurrent translocations in leukemia and lymphoma. It also undergoes mutations in 60% of adult acute myeloid leukemia (AML) cases with normal karyotype. The incidence and significance of NPM1 deletion in human leukemia have not been elucidated....

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: La Starza, Roberta, Matteucci, Caterina, Gorello, Paolo, Brandimarte, Lucia, Pierini, Valentina, Crescenzi, Barbara, Nofrini, Valeria, Rosati, Roberto, Gottardi, Enrico, Saglio, Giuseppe, Santucci, Antonella, Berchicci, Laura, Arcioni, Francesco, Falini, Brunangelo, Martelli, Massimo Fabrizio, Sambani, Constantina, Aventin, Anna, Mecucci, Cristina
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Public Library of Science 2010
Gaiak:
Research Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2943467/
https://ncbi.nlm.nih.gov/pubmed/20877721
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0012855
Etiketak: Etiketa erantsi
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!

Antzeko izenburuak