Caricamento...

Cholesterol Pathways Affected by Small Molecules That Decrease Sterol Levels in Niemann-Pick Type C Mutant Cells

BACKGROUND: Niemann-Pick type C (NPC) disease is a genetically inherited multi-lipid storage disorder with impaired efflux of cholesterol from lysosomal storage organelles. METHODOLOGY/PRINCIPAL FINDINGS: The effect of screen-selected cholesterol lowering compounds on the major sterol pathways was s...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Autori principali: Rujoi, Madalina, Pipalia, Nina H., Maxfield, Frederick R.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2010
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2943465/
https://ncbi.nlm.nih.gov/pubmed/20877719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0012788
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !